Terpin Hydrat

Terpin Hydrat

Giá: Liên hệ
Tình trạng kho: còn hàng

Mô tả

1. Các loại tên và công thức của thành phẩm.

-         Tên gọi : Tecpin hydrat (VN).
-         Tên gọi khác : Terpin hydrate; terpinol (cis-terpin hydrate); Terpinum; Terpina; Terpirmm Hydratum. Fr. Terpine; Dihydrate de terebenthene; Hydrate de dipentene; Cisterpine; Hydrate de terpine. Ger. Terpinhydrat. It. Terpina idrata; Idrato di terpina. Sp. Terpina; Hidrato de terpina. Terpin Hydrate; Terpini Hydras; Terpin. Hyd; p-Menthane-1,8-diol.
-         Có 2 đồng phân hình học : cis- và trans- .
-         CAS Registry Number:  2451-01-6 (cis-terpin hydrate); 565-50-4 (trans- terpin hydrate).
-         CAS name : Cyclohexanemethanol, 4-hydroxy-a,a-4-trimethyl-, monohydrate.
-         Công thức phân tử : C10­H20O2.H2O.
-         Khối lượng phân tử : 188.74 kg/kmol.

2. Tính chất vật lý.

·        Cis-terpin hydrate :
-         Dạng tồn tại :  Tinh thể hình chóp.
-         Nhiệt độ nóng chảy : 116-117°; thăng hoa ở khoảng 100° khi làm nóng từ từ.
-         Tính chất : Có mùi nhẹ, đặc trưng; vị hơi đắng; ở dạng bột, xốp trong không khí khô.
-         Độ tan : 1 gam tan trong 34 ml nước sôi, 13 ml cồn, 3 ml cồn sôi, 135 ml clorofooc, 140 ml ete, ~1 ml axit axetic (dạng băng) sôi.  Ở 20°C, 1 g tan trong 13 ml metanol, 13 ml ety axetat, 250 ml nước, 77 ml benzen, 290 ml CCl4, 250 ml CS2.  Không tan trong ete dầu.
-         Nhiệt độ sôi :  khoảng 258°C.
·        Trans-terpin hydrate :
-         Tinh thể dạng lăng trụ đơn tà.
-         Nhiệt độ nóng chảy : 158-159°.
-         Độ tan : Ở 20° 1 gam tan trong 11 ml metanol, 20 ml etyl axetat, 100 ml nước, 250 ml benzen, 250 ml CCl4, 500 ml CS2.

3. Ứng dụng.

- Terpin hydrate được sử dụng trong điều trị các chứng viêm phế quản cấp và mãn tính.
- Có thể được sử dụng kết hợp với một số chế phẩm khác. VD : Codein trong điều trị ho do viêm phế quản.
- Dùng hỗn hợp với Codein, viên terpin codein làm thuốc ho long đờm, chữa viêm loét, các niêm mạc thuộc đưòng hô hấp.
- Dạng cis hidrat thường được sử dụng trị ho long đờm.
- Thường được kết hợp với Codein, Natri benzoate có tác dụng chữa  ho, long đờm trong điều trị viêm phế quản cấp hay mãn tính.
- Tăng tiết dịch khí quản (long đờm).
- Dùng để sản xuất ra Terpinneol, cineol (là sản phẩm rất có giá trị điều trị trong y học)
- Có thể sản xuất ra các tinh dầu làm hương liệu trong sản xuất nước hoa.

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